Prospects for successful treatment of Parkinson’s disease with the use of apomorphine

نویسندگان

چکیده

Optimizing the treatment of idiopathic Parkinson’s disease is a complex, multifaceted and continuous process that directly affects quality life. The main position this review need for individualized therapy provides optimal motor function with least negative consequences. Apomorphine, dopamine agonist used as emergency patients fluctuations potential positive effect on non-motor symptoms, only antiparkinsonian drug whose ability to control symptoms equivalent levodopa. Subcutaneous administration periodic injection most effective affordable way correct dopaminergic insufficiency in disease. data multicenter studies presented confirm high efficiency, adequate tolerability prospects apomorphine use comprehensive pathogenetic This contains historical reference generalizes structure, mechanism action, pharmacodyna-mics, indications, contraindications side effects subcutaneous injections at advanced stages clinical course

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ژورنال

عنوان ژورنال: INTERNATIONAL NEUROLOGICAL JOURNAL

سال: 2021

ISSN: ['2307-1419', '2224-0713']

DOI: https://doi.org/10.22141/2224-0713.17.4.2021.237604